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More than 90 percent of antibiotic, infusion and biomedical stoppers made in Europe, the United States and Asia are based on halobutyl rubber. Exxon™ halobutyl rubber is ideal for stoppers and seals because of its high cleanliness and chemical resistance as well as low permeability to air, gases and moisture.
Because halobutyl rubber is chemically inert and nonpolar, absorption of drugs or water is low. Studies indicate that bromobutyl rubber-based stoppers have much lower drug turbidity than regular butyl stoppers.
Another option for high-end applications is Exxpro™ specialty elastomer, a brominated isobutylene paramethyl-styrene terpolymer (BIMSM). It is the cleanest elastomer available from ExxonMobil that is suitable for pharmaceutical applications. Exxpro specialty elastomer-based stoppers have been shown to exhibit similar drug turbidity performance in comparison to a coated stopper.
Exxon halobutyl rubber offers a number of other advantages over natural rubber and other synthetic rubbers in pharmaceutical packaging, including:
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Exxon™ butyl rubber is the foundation of today’s butyl rubber technology. It is a copolymer of isobutylene and a small amount of isoprene. The primary properties are excellent air-barrier performance, good flex fatigue and vibration damping.
Exxon™ bromobutyl rubber is derived from halogenating butyl rubber with bromine in a continuous process. It is structurally similar to Exxon™ chlorobutyl rubber and produced through the same halogenation process.
Exxon™ chlorobutyl rubber is derived from halogenating butyl rubber with chlorine in a continuous process. It is structurally similar to Exxon bromobutyl rubber and produced through the same halogenation process.
Exxpro™ specialty elastomers, brominated isobutylene paramethyl-styrene terpolymers (BIMSM), provide a super-clean solution and cost-effective alternative to expensive coated stoppers. In the tire industry, Exxpro is used for high-performance bladders and envelopes.
Read the full brochure to learn how high-quality, uniform products, supply reliability and our level of technical support have lead to successful application development.
Model formula for pharmaceutical closure Exxpro Specialty Elastomer Grade 3433.
